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The transgene contains a CAG promoter, floxed chloramphenicol acetyl transferase gene, a fusion gene in which the Drosophila engrailed repressor domain replaces the transcription activation domain of mouse Hoxb5, an IRES sequence and an EGFP reporter gene. Cre-mediated recombination is required to achieve expression of the fusion gene. Two lines (A2 and E4) achieved germline transmission. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:136122)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
