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An 8.5 kb portion of the calcium/calmodulin-dependent protein kinase II-alpha promoter containing upstream control regions and the transcriptional initiation site drives the expression of a human wild-type tau cDNA in forebrain neurons. Western blot confirmed expression in the brain and that tau becomes hyperphosphorylated with increasing age. (J:172762)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
