The targeting construct introduced into the locus a CAG promoter driving bicistronic expression of mouse Hoxc8 cDNA and the EGFP reporter gene. Cre-mediated recombination is required to remove a floxed transcriptional stop sequence and neomyocin resistance cassette between the promoter and expressed sequences. (J:227707)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count