The transgene contains the mouse transthyretin promoter driving expression of human SMYD3 (SET and MYND domain containing 3) with three hemagglutinin (HA) and three FLAG epitope tags at its C- and N-termini, respectively. Hepatic expression of the human protein is at least 15-fold that of the endogenous mouse protein. (J:82809)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count