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A C-to-T point mutation located in exon 47 results in a premature stop codon at the arginine codon (p.R2034*). This results in reduced levels of mRNA and absence of detectable levels of protein in bone marrow derived dendritic cells from homozygous mice. This mutation was found in mice carrying Nlrp10tm1Seis (J:220239)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
