An FRT-flanked neomycin resistance cassette and a loxP-Stop-loxP-IRES-DTR (human diptheria toxin receptor)-mCherry element were introduced to exon 5, immediately after the stop codon. The mCherry is not expressed effectively after excision of the excision of the Stop element and mice should not be used as reporter animals. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:230709)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6(Cg)-Tyrc-2J
Targeted
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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