A loxP site and an FRT flanked pgk-neo cassette in inverse orientation were inserted into intron 6 and a loxP site was inserted intron 7. Flp mediated recombination removed the neo cassette leaving exon 7 floxed. (J:219506)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count