Log In|Sign Up
EN
Cre-mediated recombination removed the loxP flanked exon 3, causing a frameshift mutation at the splice junction site across exons 2 and 4. This results in disruption of 3 transmembrane motifs and an ATP-binding domain that is encoded by the downstream region of exon 3. Western blot analysis confirmed absence of protein in homozygotes. (J:223428)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
