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This transgene, which contains the human heme oxygenase 1 (HMOX1) coding sequence downstream of the tetracycline response element, comprising seven tandem copies of the tetracycline operator, permits tissue-specific, doxycycline-inducible expression of HMOX1 in mice also bearing a tissue-specific reverse tetracycline transactivator (rtTA) transgene. (J:82809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
