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Recombination using Gt(ROSA)26Sortm2Bgh replaced the hygromycin resistance cassette is replaced with tetracycline response element driving inducible expression of a tdTomato reporter gene, 2A peptide sequence and a human BRAF cDNA with the point mutation that results in the amino acid substitution of lysine for valine at position 600 (V600K) followed by a polyadenylation sequence. (J:222531)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
