A loxP site was inserted in intron 6 upstream of exon 7, a neomycin selection cassette flanked by FRT sites in intron 9 followed by a loxP site. The neomycin cassette was removed via Flp-mediated recombination leaving exons 7-9 flanked by loxP sites. (J:226997)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count