LoxP sites were introduced into intron 1 and intron 4. The positive selection cassette used for targeting was removed via FLPe mediated recombination after germline transmission. (J:228346)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count