A loxP site was inserted upstream of exon 5. An FRT-flanked selection cassette with a 3' loxP site were inserted downstream of exon 6. Flp-mediated recombination removed the selection cassette and left exons 5 and 6 floxed. (J:225221)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count