The targeting vector introduced into exon 19 the cDNA for the terminal portion of the beta isoform, a human beta-globin splice and floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:221627)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count