The MDR1-luc transgene was designed to contain approximately 10 kb of 5'-flanking sequences from the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 locus (ABCB1; including the promoter and regulatory nuclear response elements) upstream of a firefly luciferase sequence (luc). (J:227043)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count