The targeting construct introduced the substitution of a termination codon for tryptophan at position 16 (W16X). Cre-mediated recombination removed the floxed neomycin resistance cassette introduced downstream of the coding sequence. (J:225022)
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The targeting construct introduced the substitution of a termination codon for tryptophan at position 16 (W16X). Cre-mediated recombination removed the floxed neomycin resistance cassette introduced downstream of the coding sequence. (J:225022)