A loxP site upstream of exon 2, a frt site, a loxP site, a neomycin selection cassette, a frt site, and a loxP site were inserted downstream of exon 4 via homologous recombination. The neomycin selection cassette was removed via flp-mediated recombination. (J:222181)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count