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A targeting vector was designed with a minimal adenovirus type 2 major late splice acceptor, a loxP-flanked Neo-STOP cassette, a cDNA sequence encoding human GNAQ* (a mutant form of GNAQ rendered constitutively active by substitution of Glutamine 209 for Leucine (Q209L), and a bovine growth hormone polyadenylation signal. (J:225597)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
