A single loxP site was inserted 5' to exon 3 and a loxP/FRT-flanked neomycin resistance cassette was inserted 3' to exon 3 via homologous recombination. Flp-mediated recombination deleted the neo cassette leaving exon 3 floxed. (J:222206)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count