The targeting vector is designed to insert a loxP site upstream of the Mir182 coding region and a FRT-flanked neomycin resistance (neo) cassette downstream of the coding region followed by a second loxP site. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:217635)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count