A targeting vector containing a loxP-flanked exon 2 of and an FRT-flanked puromycin selection cassette was intregrated into the locus by homologous recombination. Subsequently, the selection cassette was removed by flpe recombination. (J:227618)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count