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EN
The targeting vector is designed to insert downstream of the first non-coding intron with (from 3' to 5') an FRT site, engrailed 2 intron and exon with splice acceptor site, H2B-Venus-polyadenylation sequence, rox-flanked beta actin promoter driven NEO cassette, and a loxP site, followed by exon 2 and a second loxP site. Two alternative translation initiation codons are present in exon 2. (J:226600, J:227467)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
