Log In|Sign Up
EN
A lacZ gene and loxP-flanked neomycin resistance cassette was inserted in-frame into the endogenous locus. RT-PCR analysis on RNA derived from homozygous embryos showed that a transcript from this allele is undetectable. A complete loss of encoded protein was shown with antibodies to both the N and C terminus of the protein. (J:226733)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
