The transgene contains the sensory ganglion-specific enhancer of the Six1 homeobox gene (Six1enh8), the HSV thymidine kinase gene promoter, a chimeric intron a cre recombinase gene with a nuclear localization signal that are flanked by two tandem copies of the core region of the HS4 insulator. Lines 22L, 30L, 31L, 32L, 33L, 7l and 35l were generated. Line 35l is also designated as line 2 and was selected as the representative line. (J:227250)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x DBA/2J)F1
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Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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