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This transgene comprises a single, stably integrated copy of a pTRIP deltaU3-derived lentiviral vector containing the coding sequences for green flourescent protein (GFP) and mouse FK506 binding protein 11 (FKBP11, also called FKBP19) under transcriptional control of the human ubiquitin C (UBC) gene promoter. A DNA segment between the GFP and Fbkb11 sequences that encodes a "self-cleaving" picornavirus T2A peptide results in stoichiometric coexpression of the two proteins. (J:227176)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
