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A 33.5-kb DNA segment containing the mouse checkpoint kinase 1 (Chek1) gene and 5' and 3' flanking sequences extending to the next conserved gene in either direction was subcloned into a minimal vector, which was then linearized for microinjection into fertilized oocytes. Southern blot analysis revealed that one line had integrated a single copy of the transgene. (J:182697)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
