The targeting vector contains a loxP site upstream of exon 2 and an FRT-flanked neomycin selection cassette followed by a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 2 and 3 floxed. (J:226899)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count