Log In|Sign Up
EN
The murine gene with a single point mutation of G to A in exon 12 that is confined to Asians and results in a substitution of glutamine 487 to lysine (E487K) is under the control of the human elongation factor-1 alpha. This mutation results in a dominant-negative effect. Three lines were established: DAL101, DAL102, and DAL103. DAL101 is the high expressing line. (J:137374)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
