The targeting vector inserted into the locus a CAG promoter, floxed STOP sequence, Venus reporter gene, tripleF2A (three tandem repeats of foot-and-mouth disease 2A peptide sequence), Sdk2 gene, WPRE sequence and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the neomycin resistance cassette. (J:225578)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count