The first coding exon was replaced with an inducible cre recombinase gene (cre/ERT2) epitope tagged with three tandem copies of haemagglutinin (HA). Cre-mediated recombination removed the floxed neomycin resistance cassette. Immunohistochemistry confirmed the absence of protein expression in the retina from P30. (J:225578)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count