Two loxP sites were inserted upstream and downstream of the coding region of 19a. A PGK-Neo cassette, flanked by two FRT sites was inserted upstream of 19a in intron 18 next to the loxP site. The neomycin selection cassette was removed via Flp-mediated recombination. (J:221309)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count