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A loxP-flanked neomycin selection cassette replaced a genomic fragment containing exon 10. The neomycin cassette was removed via Cre-mediated recombination. This allele mis-expresses the 3R-tau isoform after P18 in heterozygous and homozygous mice, when it is not seen in wild-type mice. 4R-tau isoform expression is unaffected. (J:221311)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
