The targeting construct inserted in frame with exon 1 an improved cre recombinase gene (icre), IRES, nuclear lacz reporter gene and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the recombinase gene. (J:226614)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count