The targeting vector is designed to have a loxP site upstream of exon 2, and an FRT-flanked neo cassette followed by a second loxP site just downstream of exon 4. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 2 through 4 floxed. (J:229516)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count