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The transgenic construct contains cDNA of human alpha B crystallin under the control of the mouse Prnp, prion protein, gene promoter. The 6 kb promoter consists of the first exon, the first intron, and the fused 2nd and 3rd exons. Expression of the transgene is observed in the forebrain, cerebellum, spinal cord and kidney. No evidence of expression was found in lung, spleen, testes or liver. (J:226527)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
