LoxP sites were inserted into the PvuII site in intron 1 and into the KpnI site in intron 7. In addition, a neomycin resistance (Neo) cassette, flanked by two FRT sites, was inserted into the PvuII site in intron 1. Resulting animals were then bred with FLPe-expressing mice resulting in the deletion of the Neo cassette. (J:217695)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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