The targeting construct inserted into the locus a CAGGS promoter, loxP site, lox511 site, an inverted Rspo3 sequence, loxP site, lox511 site, polyadenylation sequence and FRT-flanked puromycin resistance cassette. Cre-mediated recombination is needed to restore correct orientation of the coding sequence under control of the upstream ubiquitous CAGGS promoter. (J:309330)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
--
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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