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The targeting construct inserted into the locus a CAG promoter; floxed STOP cassette; an HA tagged mutant G protein-coupled receptor (GPCR) sequence of the Galphas-coupled rat muscarinic 3 DREADD (designer receptor exclusively activated by designer drug), also referred to as R-s; a GFP reporter gene; and a cAMP responsive element activated by cAMP that drives expression of a luciferase reporter gene. (J:239137)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
