LoxP sites were inserted, with an adjacent FRT flanked neomycin resistance cassette, upstream and downstream of exon 4. Mice were subsequently mated to flp expressing mice to remove the neo cassette. (J:194266)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count