A loxP site was inserted in intron 2 and an FRT flanked pgk-neo cassette in inverse orientation and loxP site were inserted in intron 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:217104)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count