The first loxP site was inserted into intron 10 followed by a loxP-flanked neo cassette in intron 15. Recombinase-mediated recombination removed the neo cassette, leaving exons 11-15 floxed. (J:223761)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count