Exons 4-10 were replaced by an IRES-lacZ-SV40pA (beta-galactosidase) marker and a PGK-Neomycin-bGHpA selection cassette. Northern blot analysis indicated that no detectable transcript encoding the C-terminus is expressed from this allele. The N-terminus is expressed together with the introduced lacZ gene. LacZ is expressed in Sertoli cells. (J:225512)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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