A targeting vector was designed to insert a loxP site upstream of exon 1 and a second loxP site downstream of exon 1 followed by an FRT-flanked neomycin resistance (neo) cassette which included a third loxP site, downstream of exon 1. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 1 floxed. (J:225860)
Basic Information
C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count