A targeting vector was designed to insert a loxP site upstream of exon 11 and a second loxP site, followed by an FRT-flanked neomycin resistance (neo) cassette which includes a third loxP site, downstream of exon 11. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 11 floxed. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6 x 129X1/SvJ
Targeted
Insertion
--
1
7
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top