A loxP site was inserted upstream of exon 7 and a Frt-flanked neo cassette with 3' loxP sequence were inserted downstream of exon 7. Flp mediated recombination removed the neo cassette leaving loxP-flanked exon 7. (J:223478)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count