A targeting vector was designed to insert loxP sites around exon 2 and a neo cassette while inserting an inverted exon 2 with multiple stop codons downstream of the floxed sequence. (J:201547)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count