This ENU-induced mutation was isolated in a screen for cytotoxic T lymphocyte response to LCMV C13 infection. Sequencing identified an A to G transition at nucleotide 1304 in exon 2. Western blot analysis reveals increased protein expression on total CD8+ T cells following LCMV infection. (J:223336)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count