A targeting vector to insert a loxP site upstream of exon 3, containing the translation initiation sequence, and a second loxP site downstream of exon 4 of the interleukin 1 receptor, type I (Il1r1) gene. An FRT-flanked neomycin resistance (neo) cassette was placed downstream of the 3' loxP site. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:241345)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count