A loxP site was inserted into exon 22 downstream of the STOP codon. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted into exon 22 downstream of the 1.1 kb sequence to be deleted from the 3'UTR. Flp-mediated recombination removed the selection cassette. (J:222342)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count