An FRT-flanked beta-geo cassette with a transmembrane domain and a 3' loxP site. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the beta-geo cassette and left exons 3 through 5 floxed. (J:199510)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count